PUBLICATIONS & RESOURCES
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VINEx Media Coverage and Publications
JUNE 9, 2021
Report on Pan-Canadian Long Covid Impact Survey
Report on the survey conducted by Viral Neuro Exploration (VINEx), COVID Long Haulers Support Group Canada, and Neurological Health Charities Canada (NHCC) examining the impact of Long COVID.
June 3, 2021
Pan-Canadian Survey Reveals Long-term Harm of COVID to Brain Health
Viral Neuro Exploration (VINEx), COVID Long Haulers Support Group Canada, and Neurological Health Charities Canada (NHCC) announce the results of a pan-Canadian survey of more than 1,000 COVID long-haulers, revealing the impact of Long COVID on brain health.
February 5, 2021
Canada should lead the effort to help COVID long-haulers
The Globe and Mail. Inez Jabalpurwala, the global director of the Viral Neuro Exploration (VINEx) initiative, makes the case that COVID-19 research needs to include survivors of the pandemic that have a reduced quality of life and potentially lasting neurological impacts -- and that Canada can lead the way.
NOVEMBER 4, 2020
Be open to unexpected ideas: How Inez Jabalpurwala gives voice to outliers
Forbes. As the founding CEO of Brain Canada and now the global director of the Viral Neuro Exploration (known as “VINEx”), a social impact venture that was initiated by Rocket Science Health, a private medical device company, Jabalpurwala has been a catalyst, rallying and closely collaborating with a community of scientists from different fields and disciplines.
August 12, 2020
How does COVID-19 affect the nervous system? Canadian and international scientists want to find out.
The Globe and Mail. Brought together as part of a new initiative called VINEx, created by Rocket Science Health, a Victoria-based medical devices company, the group is aiming to lead the charge in understanding how viruses invade the brain – an area of study that has received relatively little attention.
August 17, 2020
How is COVID-19 affecting people's brains.
The Adam Stirling Show (CFAX 1070). There are many unknowns about Covid-19 and the effect it has on the brains of patients is one of them. Inez Jabalpurwala, Global Director for VINEx, spoke with Adam about a multi-disciplinary exploration of the virus-brain connection.
SEPTEMBER 1, 2020
Dr. Robyn S. Klein MD, PhD Joins VINEx Science Advisory Council.
Rocket Science Health today announced that Robyn S. Klein, MD, PhD, has joined the Science Advisory Council (SAC) for VINEx.
AUGUST 13, 2020
Rocket Science Health and Inez Jabalpurwala team up to launch VINEx. A Multi-disciplinary exploration of the virus-brain connection.
VINEx to Provide Catalytic Leadership for Research into a Vital Area in the Fight Against SARS-CoV-2 and other Viruses which may have Lasting Effects on the Brain.
EXTERNAL SCIENTIFIC LITERATURE
Brain imaging before and after COVID-19 in UK Biobank
Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, Frederik Lange, Jesper L.R. Andersson, Ludovica Griffanti, Eugene Duff, Saad Jbabdi, Bernd Taschler, Anderson Winkler, Thomas E. Nichols, Rory Collins, Paul M. Matthews, Naomi Allen, Karla L. Miller, Stephen M. Smith
medRxiv June 11, 2021; doi: https://doi.org/10.1101/2021.06.11.21258690
Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review
Francesca Reyes Domingo, Lisa A Waddell, Angela M. Cheung, Curtis L. Cooper, Veronica J. Belcourt, Alexandra M. E. Zuckermann, Tricia Corrin, Rukshanda Ahmad, Laura Boland, Claudie Laprise, Leanne Idzerda, Anam Khan, Alejandra Jaramillo Garcia
medRxiv, June 2, 2021; doi: https://doi.org/10.1101/2021.06.03.21258317
Attributes and predictors of long COVID
Sudre, C.H., Murray, B., Varsavsky, T. et al. Attributes and predictors of long COVID. Nat Med 27, 626–631 (2021).
Approaches to understanding COVID‐19 and its neurological associations
Beghi, E., Michael, B., Solomon, T., Westenberg, E., Winkler, A. Annals of Neurology. April 9, 2021.
doi: 10.1002/ana.26076.
6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records
LEARN MOREPost-acute COVID-19 syndrome
Nalbandian, A., Sehgal, K., Gupta, A. et al. 2021. Nature Medicine. https://doi.org/10.1038/s41591-021-01283-z
Neurological infection with SARS-CoV-2 — the story so far
Solomon, T. Nat Rev Neurol 17, 65–66 (2021). https://doi.org/10.1038/s41582-020-00453-w
The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning
LEARN MORENeuroCOVID: it's time to join forces globally
Helbok, R., Chou, S., Beghi, E., Mainali, S., Frontera, J., Robertson, C., Fink, E., Schober, M., Moro, E., McNett, M. and Bassetti, C., 2021. The Lancet Neurology.
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62,354 COVID-19 cases in the USA
LEARN MOREA systematic review of neurological symptoms and complications of COVID-19
Chen X, Laurent S, Onur OA, et al. J Neurol. 2020;1-11. doi:10.1007/s00415-020-10067-3
Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review
Zubair AS, McAlpine LS, Gardin T, Farhadian S, Kuruvilla DE, Spudich S. JAMA Neurol. Published online May 29, 2020. doi:10.1001/jamaneurol.2020.2065
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
Mao L, Jin H, Wang M, et al. JAMA Neurol. 2020;77(6):683–690. doi:10.1001/jamaneurol.2020.1127
SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection.
Butowt R, Bilinska K. ACS Chem Neurosci. 2020;11(9):1200-1203. doi:10.1021/acschemneuro.0c00172
Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Holmes, Emily A et al. The Lancet Psychiatry, Volume 7, Issue 6, 547 – 560
Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies.
Misra, S. et al. Preprint. medRxiv. April 23, 2021. https://doi.org/10.1101/2021.04.20.21255780
High-dimensional characterization of post-acute sequalae of COVID-19
Al-Aly, Z., Xie, Y. Bowe, B. Nature. April 22, 2021
From our Science Advisory Council Members
New research adds to calls for better support for long COVID patients
June 21, 2021 - Ottawa Citizen
How COVID-19 Affects the Brain
Boldrini M, Canoll PD, Klein RS. How COVID-19 Affects the Brain. JAMA Psychiatry. Published online March 26, 2021. doi:10.1001/jamapsychiatry.2021.0500
COVID-19 Neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital (PREPRINT)
Thakur K et al (Klein RS). Preprint. Published online March 21, 2021. doi.org/10.1101/2021.03.16.21253167
The impact of SARS‐CoV‐2 in dementia across Latin America: A call for an urgent regional plan and coordinated response
Ibanez A, Santamaria-Garcia H, Guerrero Barragan A, et al. Alzheimers Dement (N Y). 2020;6(1):e12092. Published 2020 Nov 23. doi:10.1002/trc2.12092
Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease
Serrano GE, Walker JE, Arce R, et al. Preprint. medRxiv. 2021;2021.02.15.21251511. Published 2021 Feb 18. doi:10.1101/2021.02.15.21251511
Potential differences in cleavage of the S protein and type-1 interferon together control human coronavirus infection, propagation, and neuropathology within the central nervous system
Alain Le Coupanec, Marc Desforges, Benedikt Kaufer, Philippe Dubeau, Marceline Côté, Pierre J. Talbot. Journal of Virology. Feb 2021, JVI.00140-21; DOI: 10.1128/JVI.00140-21
Microvascular Injury in the Brains of Patients with Covid-19
Lee M-H, Perl DP, Nair G, et al. New England Journal of Medicine. 2021;384(5):481-483. doi:10.1056/nejmc2033369
Neurological issues during COVID-19: An overview
Nath A, Smith B. Neurosci Lett. 2021;742:135533. doi:10.1016/j.neulet.2020.135533
Is COVID-19 a Perfect Storm for Parkinson's Disease?
Brundin P, Nath A, Beckham JD. Trends Neurosci. 2020;43(12):931-933. doi:10.1016/j.tins.2020.10.009
Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System.
Desforges M, Le Coupanec A, Dubeau P, et al. Viruses. 2019;12(1):14. Published 2019 Dec 20. doi:10.3390/v12010014
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Central Nervous System
De Felice, Fernanda G. et al. Trends in Neurosciences, Volume 43, Issue 6, 355 – 357
Neurologic complications of coronavirus infections.
Nath, Avindra. Neurology. May 2020, 94 (19) 809-810; DOI: 10.1212/WNL.0000000000009455
News Resources - Neurological effects of COVID-19
It’s Not Over ’Til It’s Over: Prevalence Of Long-Term Symptoms In Individuals Diagnosed With Covid-19
based on the following journal article:
Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review
June 15, 2021 - COVID-19 Immunity Task Force
Cleveland Clinic-led Study Identifies How COVID-19 Linked to Alzheimer’s Disease-like Cognitive Impairment
June 10th, 2021 - Cleveland Clinic Newsroom
Scientists begin to unravel the mysteries of the coronavirus and brains
June 7th, 2021 - Washington Post
Understanding The Neurological And Psychological Effects Of Covid-19
April 29, 2021 - Forbes
Covid-19 gave scientists an opening to better understand how brain disorders arise
April 26, 2021 - Stat
Une étude montréalaise pour mieux comprendre la COVID-19 longue
April 16, 2021 - Quebec Science
A Close Look at How COVID-19 Infection Can Damage the Brain
April 15, 2021 - Brain and Behavior Research Foundation Blog
Psychiatric and neurological problems are common in COVID-19’s wake, study finds
April 8, 2021 - Los Angeles Times
'Brain fog' and other neurologic symptoms can last for months after Covid
March 23, 2021 - NBC News
In the wake of the pandemic: preparing for Long COVID (2021)
February 25, 2021 - WHO policy Brief
COVID-19 Could Increase Dementia, Other Brain Disorders for Decades to Come
February 10, 2021 - Newsweek
Taking a Closer Look at COVID-19’s Effects on the Brain
January 14, 2021 - NIH Director's Blog
COVID-19 long-haulers: Canada's forgotten patients
January 23, 2021 - CBC Marketplace
Related Article: 60% of COVID-19 long-haulers say government is 'absolutely ignoring them,' Marketplace questionnaire finds. CBC
We're about to see a wave of long Covid. When will ministers take it seriously?
January 21, 2021 - The Guardian
One in 5 COVID-19 patients develop mental illness within 90 days -study
November 9, 2020 - Reuters
Covid Survivors With Long-Term Symptoms Need Urgent Attention, Experts Say
December 4, 2020 - New York Times
Long after the fire of a Covid-19 infection, mental and neurological effects can still smolder
August 12, 2020 - Stat
'I Feel Like I Have Dementia’: Brain Fog Plagues Covid Survivors.
October 11, 2020 - New York Times
ORGANIZATIONS OF INTEREST
Long-COVID Alliance
LEARN MORECOVID Long Haulers Support Group Canada
LEARN MOREInternational Severe Acute Respiratory and Emerging Infection Consortium
LEARN MORESurvivor Corps
A grassroots organization to connect and mobilize COVID-19 survivors to engage in research studies to further our understanding of long-term effects of the disease.