Human Factors in Intranasal Drug Delivery: New Research Validates Rocket Science Health’s Device Compatibility with Diverse Nasal Anatomies
Author: Rocket Science Health
Examples of Different Anatomies and Relevant Nasal Measurements
Designing intranasal drug delivery devices can be challenging due to significant differences in human nasal anatomy. Variations in nasal size and shape can lead to poor device fit, discomfort during use, and inconsistent drug delivery. These human factors often limit the effectiveness and adoption of intranasal devices.
Rocket Science Health set out to solve this issue with a patient-centered approach. By putting Human Factors first, we aimed to design a device that works for everyone, optimizing for usability, comfort and accessibility. This includes accommodating patients with less common nasal anatomies, and those with physical and cognitive impairments.
Study Overview
To validate the device design, Rocket Science Health conducted an evaluative Human Factors study in partnership with Research Collective, a team of Human Factors research specialists dedicated to making medical products useful, desirable and safe. The goal of this research was to demonstrate that Rocket Science Health’s device fits and functions across the broadest range of adult nasal anatomies. By identifying key nasal features and dimensions most likely to challenge the device’s fit, Rocket Science Health was able to test how the device performs across the real-world spectrum of nasal features.
Key Findings: Rocket Science Health’s Intranasal Delivery Device is One-Size-Fits-All
The comprehensive Human Factors study yielded compelling results, validating the effectiveness of Rocket Science Health's patient-centered design. These findings highlight the device's broad compatibility with diverse nasal anatomies, including:
• Universal Fit, Comfort, and Usability: Regardless of nose size or shape, all participants were able to comfortably insert, position, and operate the device correctly on the first try.
• Intuitive Operation: No participants identified challenges operating the device.
• Strong User Acceptance: Study participants indicated that they would use the device themselves.
Why it Matters
This study confirms that Rocket Science Health’s device provides a comfortable, reliable fit for adults with a wide range of nasal anatomies. By prioritizing Human Factors and real-world usability, Rocket Science Health has created an innovative medical technology poised to enable consistent, targeted drug delivery across diverse populations.
The findings of this Human Factors study build on recently published research from the University of British Columbia that demonstrate that Rocket Science Health’s patented technology outperforms traditional nasal sprays in delivering certain advanced therapeutics to the olfactory cleft. You can read more about the findings of that research here: Pioneering Precision: New Research Shows Rocket Science Health’s Laminar Fluid Ejection Device Leads in Therapeutic Drug Delivery.
Collectively, the results of these studies further advance Rocket Science Health’s progression towards advancing innovative, patient-centered solutions in the treatment of brain and central nervous system disorders.
Rocket Science Health is currently evaluating the licensing of its technology to developers where precision delivery and broad compatibility are potential success factors in pending clinical trials. Pharmaceutical, biotech, and research organizations interested in exploring precision intranasal drug delivery are encouraged to connect with us to explore opportunities for mutually beneficial collaboration.
Rocket Science Health gratefully acknowledges Research Collective’s partnership in making this research possible.
Learn More about Research Collective
About Rocket Science Health
Rocket Science Health, founded by Canadian business leader Kenneth Irving, develops precision drug delivery technologies focused on brain-targeted therapeutics and vaccines. Our needle-free intranasal device enables non-clinical self-administration for at-home care, emergency rescue, and mass immunization. Its fluidics are specifically engineered for today’s delicate biologics and dose-dependent drugs. As a team, we are driven to create innovations that expand access to care—especially for under-resourced communities and for individuals who face physical, cognitive, or challenging care environments where thoughtful design can improve health outcomes.
